Ampicillin & Cloxacillin 4 gm Veterinary Injection is a sterile high-dose beta-lactam antibiotic combination supplied as a 4,000 mg total-strength vial, containing Ampicillin 2,000 mg and Cloxacillin Sodium 2,000 mg It is formulated for veterinary therapeutic use in large livestock requiring treatment for susceptible serious bacterial infections.

The formulation may be used for the management of severe gram-positive and gram-negative systemic infections, heavy mastitis infections, severe soft-tissue infections, and respiratory sepsis, where specifically indicated by the approved veterinary product label. Ampicillin provides broad antibacterial activity, while cloxacillin offers resistance to certain beta-lactamases produced by susceptible bacteria. The sterile powder should be reconstituted as directed before administration.

Active Ingredient Function:
Ampicillin and cloxacillin are beta-lactam antibiotics that act by interfering with bacterial cell-wall synthesis, resulting in the destruction of susceptible bacteria. Ampicillin provides activity against susceptible gram-positive and gram-negative organisms, while cloxacillin provides additional activity against certain beta-lactamase-producing susceptible bacteria, particularly staphylococci.
Key Features:

Sterile high-dose veterinary antibiotic injection
Total strength: 4,000 mg per vial
Contains Ampicillin 2,000 mg
Contains Cloxacillin Sodium 2,000 mg
Beta-lactamase-resistant antibiotic combination
Intended for serious susceptible bacterial infections
May be used for severe mastitis and systemic infections, where labelled
Suitable for severe soft-tissue and respiratory infections, where indicated
Powder-for-injection formulation requiring reconstitution
Deep IM or slow IV administration according to veterinary protocol

Composition per vial:

Ampicillin — 2,000 mg
Cloxacillin Sodium — 2,000 mg
Total antibiotic content — 4,000 mg
Dosage form:** Sterile powder for injection

Important:

This is a veterinary prescription antibiotic intended for animal use only. Reconstitute strictly according to the manufacturer's instructions and administer according to the approved species-specific, weight-based dosage and treatment schedule. Use only by the labelled deep IM or slow IV route. Do not administer to animals with a known hypersensitivity to penicillins or other beta-lactam antibiotics. Monitor for allergic or hypersensitivity reactions after administration. Antibiotic therapy should be based on appropriate veterinary assessment and susceptibility considerations where practical. For food-producing livestock, strictly observe all applicable meat and milk withdrawal periods specified on the product label. Do not exceed the recommended dose or use outside the approved species and indications.